It has been talked about the possibility of the X-Men and Fantastic Four coming back to the Marvel family, most recently Stan Lee said in an interview that sooner rather than later the rights will be back to the MCU. In my opinion If they can do that as soon as possible it will be mind blowing.
Finally giving other characters more opportunities to shine and evolve them to bigger levels. I actually have a picture made in Photoshop of Spiderman and Deadpool on a bench.
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